Charles L. Wilkins

Charles L. Wilkins

Distinguished Professor, Analytical Chemistry

J. William Fulbright College of Arts & Sciences

(CHBC)-Chemistry & Biochemistry

Phone: 479-575-3160

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Continuing technological developments combine to permit the design and implementation of new approaches to chemical analysis. The unifying theme of our research program is development and demonstration of new analytical methods taking advantage of these opportunities for organic chemical analysis in the broadest sense. Applications of the new techniques range from synthetic polymer characterization to bioanalytical to environmental problems.

A major research interest involves development of Fourier transform mass spectrometry (FTMS) as a rapid, specific, and sensitive analytical tool, especially for high mass analysis. Recent research emphasizes the general areas of laser desorption and matrix-assisted laser desorption, ultimately aimed at applications involving analysis of non-volatile and/or high mass compounds with masses as large as 50,000 or more. This research is also devoted to developing fundamental understanding of the processes involved and employs a variety of lasers with wavelengths from the ultraviolet through the infrared. A project currently underway is the construction of an aerosol Fourier transform mass spectrometer, which will make possible analysis of single size-selected particles. The new instrument, that employs a 3 Tesla Oxford magnet, will be applied to both environmental and bioanalytical applications. An additional 3 Tesla FTMS and a 7 Tesla FTMS equipped with an IonSpec Omega 2001 Data Station are available for other laser desorption FTMS studies. An external source 9.4 Tesla FTMS equipped for both electrospray and MALDI is available. Also available are a TOF-TOF instrument and a Q-TOF ESI system.

Ph. D., University of Oregon, Eugene
B.S., Chapman College

Miladinovic, S. M., C.J. Kaeser, M.M. Knust, C.L. Wilkins. “Tandem Fourier Transform Mass Spectrometry of Block and Random Copolymers,” Internat. J. Mass Spectrom. 301, 184-194 (2011).

Smeal, J., C.L. Wilkins, “Imaging Mass Spectrometry,” Appl. Spectroscopy Rev., 6, 425-439 (2011) .

V. De Vriendt, S. M. Miladinovic, J. L. Colaux, F. Maseri, C. L. Wilkins, and S. Lucas, “Growth Mechanisms Involved in the Synthesis of Smooth and Microtextured Films by Acetylene Magnetron Discharges,” Langmuir, 27, 4979-4985 (2011).

C.L. Wilkins and Sarah Trimpin, Eds. “Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications.” CRC Press, Boca Raton, Florida (2011).

S.M. Miladinovic, V. DeVriendt, S.A. Robotham, F. Maseri, St. Lucas, C.L. Wilkins, “Laser Desorption/Ionization Fourier Transform Mass Spectrometry of Thin Films Deposited on Silicon by Plasma Polymerization of Acetylene,” J. Amer. Soc. Mass Spectrom., 21, 411-420 (2010). Published on www December 2009.

S.M.A.B. Batoy, S. Borgmann, K. Flick, J. Griffith, J. Jones, V. Sarawathi, A.H. Hasty, P. Kaiser, C.L. Wilkins, “Lipid and Phospholipid Profiling of Biological Samples using MALDI Fourier Transform Mass Spectrometry,” Lipids, 44, 367-371 (2009).

J. J. Jones, S. Borgmann, C. L. Wilkins, and R. M. O’Brien, “Characterizing the Phospholipid Profiles in Mammalian Tissues by MALDI FTMS,” Anal. Chem. 78, 3062-3071 (2006).

E. Pretsch, C.L. Wilkins, “Use and Abuse of Chemometrics” TrAC, Trends in Anal. Chem., 25, 1045 (2006).

J.O. Lay, R. Liyanage, S. Borgmann, C.L. Wilkins, “Problems with the “omics,” TrAC, Trends in Analytical Chem, 25, 1046-1056 (2006)

1982 Lester W. Strock Award, Society for Applied Spectroscopy 

1984 7th Annual H.W. Davis Lectures, University of South Carolina,

1984 Society of Analytical Chemists of Pittsburgh Lecture, Pennsylvania State University

1993 Tolman Medal, Southern California American Chemical Society

1994 Pittsburgh Analytical Chemistry Award

1994 Faculty Research Lecturer, University of California, Riverside

1995 Eli Lilly Distinguished Speaker in Analytical Chemistry, Indiana University

1996 New York Section of the Society for Applied Spectroscopy Gold Medal Award

1997 American Chemical Society Franklin & Field Award for Outstanding Achievement in Mass Spectrometry

1996 Elected Fellow of the American Association for the Advancement of Science

1997 Chevron Lecturer, University of California, Berkeley

2002 EAS Award for Outstanding Achievements in the Fields of Analytical Chemistry

2003 Arkansas Alumni Faculty Distinguished Achievement Award – Research

2004 University of Oregon Department of Chemistry Alumni Achievement Award, Distinguished Awardee in Pure Science

2004 University of Arkansas, Fulbright College Master Researcher Achievement Award

2006 Honorary Member, Society for Applied Spectroscopy 

2006 Fellow, Society for Applied Spectroscopy

2010 Fellow, American Chemical Society

2013 American Chemical Society Division of Analytical Chemistry Award in Chemical Instrumentation