Faculty

Yong Wang

Yong Wang

Assistant Professor

J. William Fulbright College of Arts & Sciences

(PHYS)-Physics

Phone: 479-575-4313

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SINGLE-MOLECULE & SINGLE-CELL NANOMETRIC BIOPHYSICS

Our lab works at the interface between physics, nanotechnology, and biology. We build cutting-edge biophysical tools to boost advances in biology and to gain fresh views of nature, and we observe biology and nature to inspire new physics and novel ways to apply physics.

(1) Antibiotic mechanism of metal nano-structures (nanoparticles, nanowires, and 2D materials)

(2) Dynamics of biological molecules in living systems (bacteria and animal cells)

(3) Mechanical properties of biological systems (proteins, DNA and bacteria)

(4) Development of nano-bio sensors and devices for various applications

  • PHYS 3113 - Analytical Mechanics
  • PHYS 4073 - Quantum Mechanics
  • PHYS 5773/4773 - Optical Properties of Solids
  • PHYS 5613/4613 - Introduction to Biophysics and Biophysical Techniques

 

Ph.D. - University of California Los Angeles (UCLA) - 2011

M.S. - University of California Los Angeles (UCLA) - 2007

B.S. - University of Science and Technology of China (USTC) - 2005

Selected Publications (full list)

  • Sadoon, A. A., and Wang, Y.* (2018). Anomalous, non-Gaussian, viscoelastic and age-dependent dynamics of histone-like H-NS proteins in live Escherichia coli. Physical Review E, accepted (in press).
  • Haque, M., Imamura, R., Brown, G. A., Krishnamurthi, V. R., Niyonshuti, I. I., Marcelle, T., Mathurin, L. E., Chen, J.#, and Wang, Y.* (2017). An Experiment-Based Model Quantifying Antimicrobial Activity of Silver Nanoparticles on Escherichia coliRSC Advances, 7: 56173-56182. [pdf]
  • Jiang, S., Park, S., Challapalli, S.D., Fei, J. and Wang, Y.* (2017). Robust Nonparametric Quantification of Clustering Density of Molecules in Single-Molecule Localization Microscopy. PLOS ONE, 12(6): e0179975. [pdf]
  • Wang, Y.*, Penkul, P., and Milstein, J. N.* (2016). Quantitative localization microscopy in combination with DNA smFISH reveals new features of the organization of high-copy number plasmids in bacteria, Biophysical Journal, 111:467–79. [pdf]
  • Wang, Y., Liu, Y., DeBerg, H. A., Nomura, T., Hoffman, M. T., Rohde, P. R., Schulten, K., Martinac, B., and Selvin, P. R. (2014). Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel. eLife, 3, e01834. (In the News) [pdf]
  • Wang, Y., Fruhwirth, G., Cai, E., Ng, T., and Selvin, P. R. (2013). 3D super-resolution imaging with blinking quantum dots. Nano Letters, 13(11), 5233–5241. [pdf]
  • Wang, Y., and Zocchi, G. (2011). Viscoelastic Transition and Yield Strain of the Folded Protein. PLoS ONE, 6(12), e28097. (In the News) [pdf]
  • Qu, H., Wang, Y., Tseng, C. Y., and Zocchi, G. (2011). Critical torque for kink formation in double-stranded DNA. Phys. Rev. X, 1, 021008. [pdf]
  • Wang, Y., and Zocchi, G. (2010). Elasticity of globular proteins measured from the AC susceptibility, Phys. Rev. Lett., 105(23), 238104. (Editor’s Suggestion; highlighted by the Physics Spotlighting Exceptional Research and Materials 360) [pdf]
  • Wang, Y., and Zocchi, G. (2010). Shape of fair weather clouds, Phys. Rev. Lett., 104(11), 118502. (Invited to APS Press Conference) [pdf]

 

  • 2018–2021, National Science Foundation Grant (CBET)
  • 2018-2020, Chancellor’s Discovery, Creativity, Innovation, and Collaboration Grant
  • 2016–2019, Arkansas Biosciences Institute Grants (multiple)
  • 2014–2016, Human Frontier Science Program (HFSP) Postdoctoral Fellowship
  • 2013–2014, Center for the Physics of Living Cells (CPLC) Postdoctoral Fellowship (funded by NSF Physics Frontiers Centers)
  • 2010, University Conference Travel Grant Award, UCLA
  • 2005–2011, University Fee Fellowship, UCLA
  • 2005–2011, University Fellowship, UCLA
  • 2005–2008, University Nonresident Tuition Fellowship, UCLA
  • 2006, 2007, Physics & Astronomy Department Summer Research Award, UCLA
  • 2002, 2004, Outstanding Student Scholarship, USTC
  • 2003, Guanghua Education Scholarship, USTC